Can you use the ResMed AirSense 10 Device without humidification to help reduce the travel size?

Yes, you can use the AirSense 10 device without the humidifier.

But you need to add a side cover in place of the humidifier to reduce size and seal the end of the device. But this would possibly affect your comfort, as humidification helps keep your airway moist and makes your treatment more comfortable.

The Side Cover can be purchased separately, click here to visit the product page