ResMed AirSense 11 AutoSet CPAP Machine

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The ResMed AirSense 11 AutoSet — premium auto-adjusting CPAP on the contemporary AirSense 11 platform. Three modes: APAP, AutoSet for Her, and fixed CPAP. Touchscreen, integrated HumidAir 11, ClimateLineAir 11, 27 dB quiet, 4G data tracking.

Resmed AirSense 11 Live Luxe Promotion

The ResMed AirSense 11 AutoSet is ResMed's premium auto-adjusting CPAP machine — and the highest-selling CPAP in the AU market. Built on the AirSense 11 platform with a contemporary touchscreen design, the AutoSet uses ResMed's clinically-proven auto-adjusting algorithm to vary therapy pressure breath by breath, matching your real-time breathing patterns through every position change, every REM cycle, and every seasonal shift. Three therapy modes (APAP, AutoSet for Her, and fixed pressure CPAP) make it the single most versatile CPAP machine on the market — one machine, every therapy scenario. Includes integrated HumidAir 11 humidifier, ClimateLineAir 11 heated tube, ultra-quiet 27 dB operation, 4G cellular data tracking, and ResMed's myAir Personal Therapy Assistant for new-user onboarding.

Key Features

  • AutoSet auto-adjusting algorithm: Varies pressure breath by breath within a prescribed range — increasing when it detects airway resistance, easing off when your airway is clear. Clinically proven to deliver effective therapy at the lowest comfortable pressure.
  • Three therapy modes in one machine: APAP (auto-adjusting), AutoSet for Her (gentler pressure ramps designed for female OSA patterns), and CPAP (fixed pressure). Switch between modes as your prescription evolves — no new machine required.
  • Large colour touchscreen: Tap-and-swipe navigation replaces the AirSense 10's dial-and-button interface. Most users find it more intuitive, especially in low light.
  • Integrated HumidAir 11 heated humidifier: Built into the chassis with auto-adjusting temperature management. Adjustable humidity levels plus auto Climate Control mode.
  • ClimateLineAir 11 heated tube included: Mask-end temperature sensor maintains warm humidified air all the way to your mask, eliminating rainout (condensation in the tube).
  • Ultra-quiet 27 dB Easy-Breathe motor: About as loud as a quiet whisper — one of the quietest CPAP machines available, ideal for light sleepers and bed partners.
  • 24% smaller, ~10% lighter than the AirSense 10: Compact bedside footprint and easier to travel with than the previous generation.
  • AutoSet Response comfort setting: For users with high-pressure intolerance — gentler pressure increases for a smoother night's sleep.
  • AutoRamp with sleep onset detection: Starts at a comfortable low pressure and gradually ramps to therapy pressure once it detects you've fallen asleep.
  • SmartStart: Therapy begins the moment you breathe into the mask — no buttons to press. Stops automatically when the mask is removed.
  • Expiratory Pressure Relief (EPR): Softens pressure on exhalation for a more natural breathing feel — reduces the fighting-the-machine sensation.
  • Built-in 4G cellular + over-the-air updates: Automatic nightly therapy data upload (AU network coverage); firmware updates pushed wirelessly without USB or service visits.
  • myAir app + Personal Therapy Assistant: Interactive voice-guided videos walk you through equipment setup and mask fitting; daily therapy data and Care Check-In coaching for the first month.
  • Advanced event detection: Identifies Central Sleep Apnea (CSA), RERA (Respiratory Effort Related Arousal), and Cheyne-Stokes respiration — flagged to your clinician via the AirView portal.
  • Ambient light sensor + auto-dimming screen: Screen brightness adjusts to room light and dims automatically when therapy starts. No bedside glare.

The AutoSet Algorithm — Why It Matters

The AutoSet algorithm is the single most clinically-published auto-titrating algorithm in CPAP therapy, with decades of clinical research behind it. Unlike older auto-CPAP algorithms that respond reactively to events that have already occurred, AutoSet monitors breath-by-breath flow patterns and increases pressure before an obstruction completes — keeping your airway open with the minimum pressure required at any given moment. When your airway is stable, the algorithm reduces pressure to improve comfort. The result: more effective therapy at lower average pressures than fixed-pressure CPAP, which is why AutoSet is the default recommendation for most newly-diagnosed sleep apnea patients in Australia.

Three Therapy Modes — One Machine

The AirSense 11 AutoSet's quiet superpower is its mode flexibility. The same machine runs in three distinct therapy configurations:

  • AutoSet (APAP): Auto-adjusting pressure between your prescribed minimum and maximum. The default mode — adapts breath by breath. Recommended for most users.
  • AutoSet for Her: Auto-adjusting algorithm with gentler pressure ramps, designed for the more flow-limited and REM-dominated obstructive patterns common in female patients with mild-to-moderate OSA. Backed by ResMed's For Her clinical research program.
  • CPAP (fixed pressure): Delivers one constant pressure all night — set to your prescribed level. The same mode the AirSense 11 Elite uses exclusively.

This matters because your prescription needs may change over time — weight changes, REM sleep patterns, seasonal congestion shifts, or a switch from fixed to auto-adjusting therapy on your clinician's recommendation. With the AutoSet, you can shift modes without buying a new machine.

AirSense 11 AutoSet vs AirSense 11 Elite — Which Should You Choose?

The AutoSet and Elite share identical hardware — same chassis, same touchscreen, same humidifier, same heated tube, same data tracking, same quiet motor. The only difference is the therapy algorithm:

  • AirSense 11 AutoSet (this machine): Auto-adjusting APAP within a prescribed range, plus AutoSet for Her, plus fixed pressure CPAP mode. Maximum flexibility.
  • AirSense 11 Elite: Fixed pressure CPAP only. Simpler, slightly cheaper.

The AutoSet is the right pick for most new CPAP users: APAP therapy is generally more comfortable than fixed pressure, the For Her algorithm is the only AU machine offering gender-specific OSA therapy, and you keep the option to switch to fixed pressure mode if your prescription specifies that later. The Elite is worth considering only if you have a stable, well-titrated fixed pressure prescription and the small price saving matters to you.

AirSense 11 AutoSet vs AirSense 10 AutoSet — Which Generation?

Both machines run the same AutoSet algorithm and deliver clinically equivalent therapy. The decision usually comes down to interface preference and form factor:

  • AirSense 11 AutoSet (this machine): Touchscreen interface, contemporary design, 24% smaller, 10% lighter, over-the-air firmware updates, myAir Personal Therapy Assistant for new-user onboarding.
  • AirSense 10 AutoSet 4G: Established dial-and-button interface, slightly larger footprint, proven hardware reliability over a decade of clinical use.

The AirSense 11 is generally the better choice for new CPAP users (the touchscreen and myAir setup videos lower the learning curve). The AirSense 10 remains a strong pick for users replacing a previous AirSense 10 who prefer the familiar interface.

Prescription Pre-Set Service

If you have a CPAP prescription with specific pressure settings — whether APAP min/max or a fixed CPAP pressure — CPAP Club can pre-configure the AirSense 11 AutoSet to your prescription before shipping. Upload your prescription when you place your order and the machine will arrive set to your prescribed therapy, ready to use the first night. No need to navigate the clinician menu yourself.

Therapy Data and the myAir App

The built-in 4G cellular modem automatically uploads your therapy data after each night's session (Australian network coverage only). Therapy data appears in ResMed's myAir mobile app and online portal, showing usage hours, leak events, AHI (Apnea-Hypopnea Index), mask seal quality, and AutoSet pressure-response patterns. The Personal Therapy Assistant in the myAir app walks new users through device setup and mask fitting with voice-guided interactive videos — particularly helpful for first-time CPAP users. Your sleep clinician can also access the data remotely via AirView for therapy adjustments without an in-person appointment.

Compatibility

The AirSense 11 AutoSet works with any CPAP mask using a standard 22 mm cuff connection — the full ResMed range (AirFit F30i, F30, F40, N30i, N20, P30i, P10), Fisher & Paykel masks (Solo, Vitera, Evora, Brevida, Eson, Simplus), and Philips Respironics masks (DreamWear, Amara View). Mask not included with this listing — see the package options below for bundled deals.

What's in the Box

  • 1 × ResMed AirSense 11 AutoSet CPAP Machine (with integrated HumidAir 11 humidifier)
  • 1 × ClimateLineAir 11 Heated Breathing Tube
  • 1 × Water Chamber (HumidAir 11)
  • 1 × 65W Power Supply Unit
  • 1 × Power Cord
  • 1 × Premium Travel Bag
  • 1 × Hypoallergenic Filter (pre-installed in device)
  • Setup and User Guide
  • 5-Year Extended Warranty when registered via ResMed Sleep Vantage program (2-year base + 3-year extension)

Note: Mask not included. Package options with mask choice are available — see the Full Face Mask Package, Nasal Mask Package, or Nasal Pillow Mask Package for bundled options.

Warranty in package deals: The 5-year extended warranty applies to the AirSense 11 AutoSet machine itself (when registered). Masks supplied as part of any package carry the manufacturer's standard 90-day mask warranty (covering manufacturing defects). Masks are consumable wear items and the cushions, seals, and headgear are designed to be replaced every 6–12 months as part of normal mask maintenance.

Filters and Consumables

The AirSense 11 AutoSet uses the AirSense 11-specific filter (different shape from the AirSense 10/S9 filter — they aren't interchangeable). Replace approximately monthly:

Product FAQs

 

ResMed AirSense 10 vs. AirSense 11 Comparison

Feature AirSense 10 AutoSet AirSense 11 AutoSet
User Interface Dial and button navigation Full-color touchscreen
Dimensions (H x W x D) 116 mm x 255 mm x 150 mm 94.5 mm x 259.4 mm x 138.5 mm
Weight 1,248 g 1,130 g
Sound Pressure Level 26.6 dBA 27 dBA
Power Supply Unit 90W AC Power Supply 65W AC Power Supply
Water Capacity 380 mL to maximum fill line 380 mL to maximum fill line
Connectivity Built-in Cellular (standard models) and SD Card Built-in Cellular, Bluetooth, and SD Card
Therapy Algorithms AutoSet and CPAP modes AutoSet, CPAP, and incorporated "AutoSet for Her" algorithm
Key Features AutoRamp, EPR, SmartStart, and Climate Control Personal Therapy Assistant, Care Check-In, and Over-the-Air updates

Key Notable Differences

  • Interface Upgrade: The AirSense 11 transitions from the physical dial used on the AirSense 10 to a modern touchscreen interface.

  • Integrated Algorithm: While the "AutoSet for Her" algorithm was previously a separate dedicated device in the AirSense 10 series, it is now included as a selectable mode within the standard AirSense 11 AutoSet machine.

  • Compact Design: The AirSense 11 is slightly lighter and has a lower profile (height) compared to the AirSense 10.

  • Enhanced Support: The AirSense 11 introduces "Care Check-In" and a "Personal Therapy Assistant" via the myAir app to provide users with more coaching and support during their therapy journey.

  • Connectivity: The AirSense 11 includes Bluetooth capabilities for easier pairing with smart devices, a feature not present in the AirSense 10.

Item

Warranty Period

CPAP, bilevel and ventilation devices (including integrated humidifiers and including external power supply units).

Battery accessories (including but not limited to DC cable, PSU adapter and coupler kit).

*Important Note: Extended Warranty only applies to items that are registered with ResMed Sleepvantage.
Registration documentation is provided in packaging.

2 years (Standard)

5 years (Extended)*

Click here for full ResMed warranty details

30 Day satisfaction guarantee available on new ResMed CPAP Machines**

**ResMed Satisfaction Guarantee Terms and Conditions Apply View here

NB. Replacement items are not eligible for exchange.

Specification Detail
ResMed part number 39108 (Australian SKU)
Therapy modes AutoSet (APAP), AutoSet for Her, fixed pressure CPAP
Pressure range 4–20 cm H₂O
Auto-adjusting algorithm ResMed AutoSet — breath-by-breath adjustment, clinically-proven; AutoSet Response comfort setting for high-pressure intolerance
For Her algorithm Included — gentler pressure ramps for female OSA patterns (mild-to-moderate OSA)
Humidification Integrated HumidAir 11 heated humidifier with cleanable water chamber
Humidity settings Adjustable plus auto Climate Control mode
Heated tube ClimateLineAir 11 included — mask-end sensor, Climate Control integration
Sound level 27 dB (ultra-quiet Easy-Breathe motor)
Interface Large colour touchscreen with tap-and-swipe navigation
Comfort technologies AutoRamp with sleep onset detection, SmartStart, Expiratory Pressure Relief (EPR), AutoSet Response
Event detection Apnea, hypopnea, Central Sleep Apnea (CSA), RERA, Cheyne-Stokes respiration
Data connectivity Built-in 4G cellular (AU coverage); over-the-air firmware updates; myAir app + AirView portal
myAir features Personal Therapy Assistant (voice-guided setup videos), Care Check-In coaching, daily therapy data
Screen behaviour Ambient light sensor with auto-dim/auto-off
Power supply 65W universal voltage (100–240V AC); aircraft-rated
Dimensions 24% smaller than AirSense 10 (compact bedside footprint)
Weight ~10% lighter than AirSense 10
Air outlet 22 mm cuff (universal CPAP mask fitting)
Filter AirSense 11 series filter — standard or hypoallergenic, replace monthly
Not compatible with AirSense 10 filters (different shape) or ClimateLineAir for AirSense 10 (different connector)
Aircraft compliance FAA-compliant — approved for in-flight use
Warranty 2-year ResMed standard, extendable to 5 years via ResMed Sleep Vantage registration
SKU RES39108
Model # 39108
ARTG # 222485
UPC/EAN 619498391080
Brand ResMed
Shipping Weight 2.3700kg
Shipping Width 0.370m
Shipping Height 0.285m
Shipping Length 0.110m
Shipping Cubic 0.011599500m3

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